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DNA replication is the process of producing two identical replicas from one original DNA molecule. This biological process occurs in all living organisms and is the basis for biological inheritance. DNA is made up of two strands and each strand of the original DNA molecule serves as template for the production of the complementary strand, a process referred to as semiconservative replication. Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication. DNA replication can also be performed in vitro (artificially, outside a cell). DNA polymerases isolated from cells and artificial DNA primers can be used to initiate DNA synthesis at known sequences in a template DNA molecule. The polymerase chain reaction (PCR), a common laboratory technique, cyclically applies such artificial synthesis to amplify a specific target DNA fragment from a pool of DNA. When the replication process is complete, two DNA molecules — identical to each other and identical to the original — have been produced. Each strand of the original molecule has remained intact as it served as the template for the synthesis of a complementary strand. This mode of replication is described as semi-conservative: one-half of each new molecule of DNA is old; one-half new. Watson and Crick had suggested that this was the way the DNA would turn out to be replicated. Proof of the model came from the experiments of Meselson and Stahl. The process of Chromosomal Replication in bacteria is complex. Bacterial chromosomes are double‐stranded DNA and almost always circular. DNA replication starts at a specific sequence, the origin, on the chromosome and proceeds in two directions towards another specific region, the terminus.Number of Upcoming conferences/Workshops/Symposiums are 5 in number.Around 5 companies are there which actively involved in the process of replication and its research.
OMICS Group International is an amalgamation of Open Access publications and worldwide international science conferences and events. Established in the year 2007 with the sole aim of making the information on Sciences and technology ‘Open Access’, OMICS Group publishes 400 online open access scholarly journals in all aspects of Science, Engineering, Management and Technology journals. Symposiums: Symposium on replication of viral nucleic acids.I. Formation and properties of a replicative intermediate in the biosynthesis of viral ribonucleic acid, Symposium on replication of viral nucleic acids. II. Ribonucleic acid virus replication, Eighteenth Annual Buffalo DNA Replication and Repair Symposium, Symposium on Replication in International Studies Research, Symposium on replication of viral nucleic acids. II. Ribonucleic acid virus replication, Symposium on replication of viral nucleic acids. 3. Replication of mengovirus ribonucleic acid. Associations and Societies: 1. Association of Cellular DNA Replication 2. American Cancer Society 3. Society for DNA Fingerprinting 8 Diagnostics 4. American Medical Association Relevant Conferences 1. DNA Replication and Recombination(March 1—6, 2015 British Columbia, Canada) 2. DNA Replication as a Source of DNA Damage (30 Sep 14 - 03 Oct 14) 3. Genomic Instability (July 6-11, 2014,china) 4. 4th World congress on virology (October 06-08, 2014 San Antonio, USA) 5. 3rd International Conference and Exhibition on Clinical & Cellular immunology (September 29 - October 01, 2014 Baltimore, USA) Companies: 1. New England BioLabs IncBioline 2. Adooq Bioscience LLc 3. AMS Biotechnology 4. Merck & Co.. Inc
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This page was last updated on March 28, 2020