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In the field of drug discovery, reverse pharmacology also known as target base drug discovery (TDD),a hypothesis is first made that modulation of the activity of a specific protein target will have beneficial therapeutic effects. Screening of chemical libraries of small molecules is then used to identify compounds that bind with high affinity to the target. The hits from these screens are then used as starting points for drug discovery. This method became popular after the sequencing of the human genome which allowed rapid cloning and synthesis of large quantities of purified proteins. This method is the most widely used in drug discovery today.
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Scope and Importance:
It is a branch of biology, because it is concerned with living organisms, and as such it borrows heavily from kindred subjects like physiology and biochemistry for much of its substantive matter and experimental techniques. Pharmacology is equally related to chemistry, because it deals with chemical agents and is dependent upon knowledge of their sources and properties. Also, pharmacology is an essential part of medicine. For although a drug, in broad terms, is any chemical agent other than food that affects living organisms, in its medicinal sense a drug is any chemical agent used in the treatment, cure, prevention or diagnosis of disease
The conference had multiple sessions, Keynote presentations, panel discussions and Poster sessions. We received active participation from various scientists, researchers, students and leaders from the field of Pharmacology who made this event successful.
Various sessions were carried out with multiple presentations from speakers all around the world. Major Sessions to be discussed were:
The conference was initiated with a series of lectures delivered by both Honorable Guests and members of the Keynote forum.
According to US reporting, patient data outcome in serious deaths and life threatening cases have incidentally increased every year due to adverse drug reactions, therefore there is a need to impede serious adverse effects caused by the drugs by enhancing drug targeting through research in pharmacology.
A significant portion of R&D budgets are spent on outsourcing services (domestic and/or international) offered by the CRO industry, approximately $15 billion in 2007.This figure is expected to grow at 15% over the next seven years and should increase further with the broadening of the spectrum of services outsourced to cover the entire value chain. As outsourced services in developing countries such as China and India move up the value chain to cover phase 1/2 trials, the total contracts value may increase to $30 billion by 2015.
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This page was last updated on 14th Sep, 2015
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