As per available reports about 66 relevant journals, 40 Conferences, 1395 workshops are presently dedicated exclusively to breathing disorder and about 3040 articles are being published on Infectious Diseases.

Primary Immunodeficiency Diseases (PI) are a group of more than 200 rare, chronic disorders in which part of the body’s immune system is missing or functions improperly. While not contagious, these diseases are caused by hereditary or genetic defects, and, although some disorders present at birth or in early childhood, the disorders can affect anyone, regardless of age or gender. Some affect a single part of the immune system; others may affect one or more components of the system And while the diseases may differ, they all share one common feature: each results from a defect in one of the functions of the body’s normal immune system. Because one of the most important functions of the normal immune system is to protect us against infection, patients with PI commonly have an increased susceptibility to infection.

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Scope and Importance

The Infections may be in the skin, the sinuses, the throat, the ears, the lungs, the brain or spinal cord, or in the urinary or intestinal tracts, and the increased vulnerability to infection may include repeated infections, infections that won’t clear up or unusually severe infections. People with PI live their entire lives more susceptible to infections–enduring recurrent health problems and often developing serious and debilitating illnesses. Fortunately, with proper medical care, many patients live full and independent lives. According to the leading experts in immunology , when part of the immune system is either absent or not functioning properly, it can result in an immune deficiency disease. When the cause of this deficiency is hereditary or genetic, it is called a Primary immunodeficiency diseases (PIDD). Researchers have identified more than 150* different kinds of PIDD.

The immune system is composed of white blood cells. These cells are made in the bone marrow and travel through the bloodstream and lymph nodes. They protect and defend against attacks by "foreign" invaders such as germs, bacteria and fungi. In the most common PIDDs, different forms of these cells are missing. This creates a pattern of repeated infections, severe infections and/or infections that are unusually hard to cure. These infections may attack the skin, respiratory system, the ears, the brain or spinal cord, or in the urinary or gastrointestinal tracts. In some instances, PIDD targets specific and/ or multiple organs, glands, cells and tissues. For example, heart defects are present in some PIDDs. Other PIDDs alter facial features, some stunt normal growth and still others are connected to autoimmune disorders such as rheumatoid arthritis.

Market Analysis

Infectious diseases therapeutic market

The infectious diseases therapeutic market in US is estimated to grow at a rate of 3.37% between 2014- 2019. As per the records, 25% of deaths are mainly due to infectious diseases globally. Current market trend shows that North America has the more global market for infectious diseases therapeutics due to increasing incidence of infectious diseases and due to rise in aging population. Followed by North America highest global market is expected in Asia then followed by the Europe in the global infectious diseases therapeutics market. In Asia-Pacific region, China and India are expected to be the fastest growing infectious diseases therapeutics markets. The main reasons behind the highest global market of infectious diseases therapeutics market in the above countries is mainly due to large number of patients and due to increase in government funding. Some of the major companies playing a key role in the global infectious diseases therapeutics market are Merck & Co., Pfizer, Johnson & Johnson, F. Hoffmann-La Roche, GlaxoSmithKline Pharmaceutical, Inc., Auritec Pharmaceuticals, Novartis, Achillion Pharmaceuticals, Isis Pharmaceuticals and Gilead Sciences.

Infectious diseases diagnostics market

Market for infectious disease molecular diagnostics tests includes hospitals, blood banks, reference laboratories. North America has the highest global market for molecular diagnostics tests followed by Europe due to the market availability of the tests and high occurrence rate of various infectious diseases such as HPV, hepatitis and bacterial infections. Asia Pacific, Latin America and Middle East are expected to be the potential markets in the coming years. Major companies which play a key role in infectious disease molecular diagnostics tests market are Abbott Laboratories, Affymetrix, Inc., Becton, Dickinson and Company, bioMérieux, Cepheid, Inc., Hologic, Inc., Life Technologies, Myriad Genetics, Inc., Qiagen N.V. and others.