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Plant Metabolomics In plants, the metabolome is a compilation of all primary and secondary metabolites, and can be regarded as the final recipient of genetic information where levels of individual metabolites can influence gene expression, protein stability and metabolic fluxes.These constituents of the metabolome have a wide range of physiological roles in plants such as participating in basic functions of the living cell, contributing to cellular structural integrity, acting as mobile inter- and intracellular signals, and being involved in passive and active defence responses in plant cells. Hence, qualitative and quantitative measurements of intracellular metabolites yield critical insights into the cellular processes that control the biochemical phenotype of the cell, tissue or whole organism. Metabolites are the end products of cellular functions, and their levels can be viewed as the response of biological systems to environmental or genetic manipulation. These chemicals are integral to a better understanding of plant functions, both the everyday life of a “normal” plant, and behavior of a special plant obtained through classical breeding, mutation, or other manipulation.
Metabolomics has emerged as a functional genomics tool that together with well-established technologies for high-throughput DNA sequencing (Genomics), gene expression profiling (Transcriptomics), and protein profiling (Proteomics), has the potential to accelerate our understanding of the complex molecular interactions in biological systems. The ultimate goal of Plant Metabolomics is to study the plant system at the molecular level providing non-biased characterisation of the total metabolite pool (metabolome) of plants under specific conditions. Using Metabolomics, a better understanding of the correlation between genes and the biochemical composition of a plant tissue in response to its environment (phenotype) can be obtained, and this information can be further used to assess gene function (genotype). Additionally, and in contrast to Transcriptomics and Proteomics, Metabolomics benefits from the advantage of not being dependent on the availability of organism-specific genome information for data analysis, and Metabolomics-based methods can be applied to other biological systems without re-optimising protocols.
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Plant Metabolomics Conferences in 2015:
• Metabolomics 2015, San Francisco, California
• Plant Metabolomics Session at the ASBM Annual Meeting, Boston, Massachusetts,2015
• 2nd Australian Lipid Meeting, Wollongong, NSW, Australia
• ICMSB 2015 : XIII International Conference on Metabolomics and Systems Biology, Paris
• Systems Biology of Lipid Metabolism 2015, Breckenridge, USA
• International Conference on Systems Biology and Bioengineering (ICSBB 2015),Turkey
• Metabolomics and Epidemiology Symposium at RTI International, NC USA
Lists of Societies related to Plant Metabolomics :
• The Metabolomics Society,US
• COSMOS - COordination of Standards in Metabolomics ,UK
• Northwest Metabolomics Research Center (NW-MRC), Seattle,US
• Swedish Metabolomics Centre, Sweden
• Netherlands Metabolomics Centre.
• The International Society for Systems Biology (ISSB)
• PRiMe Platform for Riken Metabolomics
Major Plant Metabolomics and related Companies:
• AB SCIEX, USA
• Metabolomic Diagnostics Ltd, Ireland
• Chenomx ,Canada
• Phenomenome Discoveries, Canada
• Metabometrix , London
• Metabolon, USA
• Lipomics, California
This page will be updated regularly.
This page was last updated on 17th Apr, 2015
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