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Neuromuscular diseases affect the muscles and their direct nervous system control. In general, problems with CNS control can cause either spasticity or paralysis, based on the location and the nature of the problem. A large proportion of neurological disorders lead to problems with effective movement. Some examples of central disorders include cerebrovascular damage, Parkinson's, multiple sclerosis, Huntington's disease.
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Neuromuscular disorders affect the nerves that control your voluntary muscles. Voluntary muscles are the ones you can control, like in your arms and legs. Your nerve cells, also called neurons, send the messages that control these muscles. When the neurons become unhealthy or die, communication between your nervous system and muscles breaks down. As a result, your muscles weaken and waste away. The weakness can lead to twitching, cramps, aches and pains, and joint and movement problems. Sometimes it also affects heart function and your ability to breathe. Symptoms of muscle disease may include muscular weakness, rigidity, loss of muscular control, myoclonus, and myalgia. Diagnostic procedures that may reveal muscular disorders include direct clinical observations.
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More than a million people in the United States are affected by some form of neuromuscular disease, and about 40% of them are under age 18. All neuromuscular diseases are progressive in nature, and all result in muscle weakness and fatigue. Some diseases are present at birth, some manifest in childhood, and others have an adult onset. The disease may be passed down through family genetic lines, and in some cases the student may have an affected sibling, parent or other relative. At other times there isn’t a family history and the disease is the result of a spontaneous genetic mutation, an abnormal immune response or an unknown cause. Many neuromuscular diseases are genetic, which means they run in families or there is a mutation in your genes. Sometimes, an immune system disorder can cause them. Most of them have no cure. The goal of treatment is to improve symptoms, increase mobility and lengthen life
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This page was last updated on December 1, 2023