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As per available reports about 45 Journals 47 Conferences 51 Workshops are presently dedicated exclusively to Myocardial Perfusion and about 145871 articles are being published on the current trends in Myocardial Perfusion.
Myocardial perfusion scan is one of the methods of performing nuclear medicine procedure. Very amount of a radioactive substance, known as a radionuclide and also known as radiopharmaceutical or radioactive tracer, is been used during the procedure to support and assist in the examination of the tissue under this study. Specifically, the myocardial perfusion scan evaluates the heart’s function and flow of the blood. A radionuclide is a small absorbable radioactive substance that is used as a tracer, which means that it have to travel through the blood stream and is taken up or absorbed by the healthy heart muscle tissue. While doing the scan, the areas where the radionuclide has been absorbed and attained will show up differently in comparison to the areas that do not absorb it this is due to possible damage to the particular tissue from decreased or blocked blood flow. Stress myocardial perfusion scan can be used to assess the flow of blood to the heart muscle known as myocardium when it is stressed by different exercise or medication, to determine what areas of the myocardium have decreased blood flow. This is done by giving an injection of a radionuclide (thallium or technetium) into a vein in the hand or arm. There are other different types of radionuclides. When one type of radionuclide is tested on the patient, all the areas of the myocardium that have blocked or partially blocked arteries will be clearly observed on the scan as "cold spots," or "defects," because these areas will not be able to take in the radionuclide into the myocardium. Other type of radionuclide combines and get attached to the calcium that is released when a heart attack takes place, so it will accumulate in area(s) of heart where tissues has been injured, as a "hot spot" on the scan. There are two different types of myocardial perfusion scans, one that is used in conjunction with exercise and one that is used in conjunction with medication. Topics like Coronary hemodynamics in heart failure Hypertension, Myocardial viability shall be discussed.
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Scope and Importance
The study aims to discuss the relationship and difference between myocardial perfusion imaging (MPI) using SPECT and CT coronary angiography (CTCA) for diagnosis of coronary artery disease (CAD). Five hundred and four cases undergoing MPI and CTCA were comparatively analyzed, including fifty six patients undergoing invasive coronary angiography in the same period. Among patients with negative MPI results, negative or positive CTCA occupied 84.7% or 15.3%, respectively. Among patients with positive MPI, positive or negative CTCA occupied 67.2% or 32.8%, respectively. Among patients with negative CTCA, negative or positive MPI occupied 94.4% or 5.6%, respectively. Among patients with positive CTCA, positive or negative MPI occupied 40.2% or 59.8%, respectively. Negative predictive value was relatively higher than the positive predictive value for positive CTCA eliminating or predicting abnormal haemo dynamics.
During the past 2 decades, myocardial perfusion imaging (MPI) has become fully embedded in the practice of clinical cardiology. Single-photon emission computed tomography (SPECT) cameras are readily available in both the hospital and the office setting. The stress protocols for MPI, with either exercise or pharmacologic stress, are well established, straightforward, and easily implemented. And there is extensive experience in the published reports and in clinical practice regarding the application of SPECT perfusion imaging for diagnosis, prognosis, and risk stratification. Thus, in an era of technological advances in ultrasound imaging, cardiac magnetic resonance, and cardiac computed tomography, SPECT perfusion imaging is firmly established as an efficient, reliable, and relatively cost-effective procedure in the management of patients with known or suspected coronary artery disease.
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This page was last updated on 12th Sep, 2015
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