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Often in the course of drug development, infusion is used as a route of administration due to toxicity concerns, solubility issues or other factors. As the scope of infusion delivery technology expands, so does the requirement for more specialized, complex infusion models to replicate drug administration routes and regimens for humans. It supports the preclinical safety assessment of drugs intended for intravenous administration in humans.
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Scope and Importance:
The main reason for infusing a drug in humans is to achieve a constant systemic exposure with the aim of producing the desired pharmacological effect, while reducing or eliminating any potential adverse effects. In toxicology, the main reason for administering a drug by infusion is to mimic the proposed clinical route and to help establish safety margins in relation to the clinical dosing regimen.
The global in-vitro toxicology testing market is estimated to reach $17,227 million by 2018 at a CAGR of 13.5% during the forecast period (2013–2018).The global market of in-vitro toxicology testing is subdivided into industry, technology, method, application and geography. On the basis of industry, the market is further segmented into diagnostics, pharmaceuticals, chemicals, cosmetics, and food. Diagnostics is further categorized into sample and type. The largest market share was captured by the pharmaceutical industry, whereas cosmetics industry was the fastest growing industry with a double digit CAGR. The prime factor contributing to the growth of pharmaceutical industry has been the attention towards the detection of toxicity during earlier stages of development.
3. Synthetic Biology Conference, August 15-17, 2016 London, United Kingdom
4. Computational System Biology Conference, August 22-23, 2016 Philadelphia, USA
6. 5th Pharmacovigilance Conference, April 28-29, 2016 Dubai, UAE
8. 7th Pharma Conference, June 20-22, 2016, New Orleans, USA
10. Cellular & Molecular Mechanisms of Toxicity, Andover, NH
11. ACT’s Annual Meeting, Summerlin, Nevada
12. EUROTOX 2015 Congress, Porto, Portugal
13. NACCT 2016, Massachusetts, USA
14. International Congress of Asian Society of Toxicology, Korea
15. ALAMCTA 2015, Buenos Aires
16. European Congress of Toxicologic Pathology, Surrey, United Kingdom
17. SOT 55th Annual Meeting, New Orleans, Louisiana
18. Congress of the European Societies of Toxicology, Istanbul, Turkey
19. Annual Meeting and ToxExpo by SOT, New Orleans
20. Joint ESTP/BSTP Meeting, University of Surrey, UK
21. APAMT International Scientific Conference, Perth, Western Australia
22. SOFT 2015 Meeting, Atlanta
23. Annual Meeting of STOX, Telangana, India
Relevant Organization and Associations:
1. Society of Toxicology, USA (SOT)
2. Society of Toxicology of Canada
3. Latin American Association of Toxicology (ALATOX)
4. Japanese Society of Toxicology
5. Italian Society of Toxicology
6. German Society of Toxicology
8. British Toxicology Society
9. French Society of Toxicology
1. Agilent Technologies (U.S.),
2. Alere, Inc. (U.S.),
3. Bio-Rad (U.S.),
4. BioReliance (Sigma Aldrich) (U.S.),
5. Catalent Pharma Solutions (U.S.),
6. Charles River Laboratories (U.S.),
7. Covance (U.S.),
8. Cyprotex (U.K.),
9. Eurofins Scientific, Inc. (U.S.),
10. GE Healthcare (U.K.),
11. Life Technologies Corporation (Thermo Fisher Scientific) (U.S.), and
12. Quest Diagnostics (U.S.)
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This page was last updated on August 4, 2020