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The genetic code is the set of rules by which information encoded within genetic material (DNA or mRNA sequences) is translated into proteins by living cells. Biological decoding is accomplished by the ribosome, which links amino acids in an order specified by mRNA, using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time. The genetic code is highly similar among all organisms and can be expressed in a simple table with 64 entries. The code defines how sequences of these nucleotide triplets, called codons, specify which amino acid will be added next during protein synthesis.
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The various methods used for genotyping analysis include polymerase chain reaction (PCR), amplified fragment length polymorphism detection (AFLPD), random amplified polymorphic detection (RAPD) of genomic DNA, allele specific oligonucleotide (ASO) probes, DNA sequencing, restriction fragment length polymorphism identification (RFLPI) of genomic DNA, and hybridization to DNA microarrays or beads. Genotyping can be applied to humans as well as microorganisms. Genotyping of viruses or bacteria may help in tracing the origin of outbreak and thus control the spread of pathogens. Genotyping develops and provides innovative technologies that enable multiplex and parallel analysis of biological systems at the cell, protein, and gene level, facilitating the rapid translation of results into biology for a better world. Genotyping researchers face major challenge in studying rare variants most effectively. Whole-genome sequencing is preferred by some for studying rare variants, however often it is too slow and too expensive while microarrays are more cost-effective and allow for higher-throughput.
The analysts have predicted that the Global Genetic Testing market will grow at a CAGR of 10% during the forecasted period 2014-2020. The new edition of the report Genetic Testing Market Outlook 2020 highlights the market landscape, key contributing drivers of the market, emerging sectors, and the regulatory framework surrounding the genetic testing segment. The report is an outcome of an in-depth market analysis by our team of analysts. It also covers the application aspect of genetic tests in several therapeutic areas, as well as the list of genetic tests available in the market.
1. National Human Genome Research Institute
2. Center for the Advancement of Genomics
3. Carolina Center for Genome Sciences
4. Research Institute for Genetic and Human Therapy
5. New York Genome Center
6. Genetic Information Research Institute
Genomic Companies :
2. Genetic Technologies Group
4. Ambry Genetics
5. Biospyder Technologies
6. Predictive biology
8. Cypher Genomics
9. Agena Bioscience
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This page was last updated on 16th Sep, 2015
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