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Connective Tissue, group of tissues in the body that maintains the form of the body and its organs and provides cohesion and internal support. The connective tissues include several types of fibrous tissue that vary only in their density and cellularity, as well as the more specialized and recognizable variants—bone, ligaments, tendons, cartilage, and adipose (fat) tissue. Connective tissue has a broad range of study like Musculoskeletal Tissue Engineering, Rheumatic Disorders and Treatment, Various Hematologic Malignancies and their treatments which may cover another wide ranged subject, Types of leukemia.
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Scope & Importance
Connective tissue is the most ample of all the tissue types in the body. The form and shape of the body, its organs, muscles, bones and the body’s construction are determined by the properties of connective tissue. Connective tissue forms a continuous interconnected system from head to toes. Every cell in the body in fact is connected to every other cell, in a continuous matrix of connective tissue. Connective tissue fibers not only connect the cells to one another but the DNA of each cell via the cytoskeleton, which is a miniature musculoskeletal system with in the cell that also is in contact with the outer cell wall and related connective tissue. What makes it even more fascinating is the design and function of the collagen that comprises the connective tissue . It has liquid crystal properties like a semi-conductor. Every movement generates bio-electric signals. Collagen is a triple helix protein polymer like structure, which has electron transporting capabilities. These properties make the connective tissue a vital player in the body’s communication system. Hence long term mis-communication and incomplete restoration of function and tissue integrity leads to compensatory imbalanced states of health, pain, dysfunction, and a decrease of human potential.
All forms of connective tissue are composed of
(1) Extracellular fibers
(2) An amorphous matrix called ground substance
The proportions of these components vary from one part of the body to another depending on the local structural requirements. In some areas, the connective tissue is loosely organized and highly cellular; in others, its fibrous components predominate; and in still others, the ground substance may be its most conspicuous feature. The anatomical classification of the various types of connective tissue is based largely upon the relative abundance and arrangement of these components. The types of connective Tissue are loose connective tissue, fibrous connective tissue, and specialized connective tissue.
Tissue arising chiefly from the embryonic mesoderm that is characterized by a highly vascular matrix and includes collagenous, elastic, and reticular fibers, adipose tissue, cartilage, and bone. It forms the supporting and connecting structures of the body.
Connective tissue can be broadly subdivided into connective tissue proper, special connective tissue, and series of other, less classifiable types of connective tissues.
 Connective tissue proper consists of loose connective tissue and dense connective tissue (which is further subdivided into dense regular and dense irregular connective tissues.)
 Special connective tissue consists of reticular connective tissue, adipose tissue, cartilage, bone, and blood.
 Other kinds of connective tissues include fibrous, elastic, and lymphoid connective tissues
The prevalence and incidence of connective tissue disorders reported are quite variable based on differences in study procedure. Most significant differences are the study duration, the classification criteria used for diagnosis and the country in which the study was undertaken. Sjögren's syndrome has the highest occurrence ranging between 0.5 and 3% of a given population. The incidence of systemic lupus erythematosus (SLE) is estimated between 15 and 50 per 100 000 persons, with a female to male ratio of 10:1 in the age group between 15 and 40 years. The occurrence of systemic sclerosis is lower, however, varying considerably between different studies and countries. The occurrence of overlap syndromes, particularly mixed connective tissue disease, is unknown, and polymyositis and dermatomyositis are observed as very rare rheumatic diseases. Though the classification criteria for the connective tissue disorders have not been established for the purpose of diagnosing an individual patient, these criteria still are the most valuable tool for the identification of patients with systemic rheumatic diseases such as connective tissue disorders.
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This page was last updated on 12th Sep, 2015
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