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As per available reports about 43 relevant Journals, 38 Conferences, 3 Workshops are presently dedicated exclusively to chronotherapetius and about 335 articles are being published on Chronotherapeutics.
Chronotherapeutics refers to a treatmentmethod in which in vivo drug availability is timed to match rhythms of disease in order to optimize therapeutic outcomes and minimize side effects. The term "chrono" basically refers to the observation that every metabolic event undergoes rhythmic changes in time. Researchers have concluded that all living organisms are composites of rhythms with varying frequencies that may range from seconds to seasons. It refers to drug bioavailability , risk factor, pharmacologic sensitivity, and pharmacokinetics of many drugs.
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Scope and Importance:
Chronotherapeutics conference provides the scope for opportunities to learn progressed by international scientists and academicians. So many symposiums have been conducted and are to be organized all across the globe focusing on the significance of Bioequivalence Innovations, Therapeutic Possibilities and Technological Challenges is going to be organized which will focus on Bio availabilty of drug .
Chronotherapeutics : The term "chrono" basically refers to the observation that every metabolic event undergoes rhythmic changes in time. Researchers have concluded that all living organisms are composites of rhythms with varying frequencies that may range from seconds to seasons.
Perhaps the best known and studied chronobiologic frequency is the circadian rhythm which approximates the earth's 24-hour rotation around the sun . Researchers have recently concluded that both disease states and drug therapy are affected by a multitude of rhythmic changes that occur within the human body . Chronotherapeutics refers to a treatmentmethod in which in vivo drug availability is timed to match rhythms of disease in order to optimize therapeutic outcomes and minimize side effects. It is based on the observation that there is an interdependent relationship between the peak-to-trough rhythmic activity in disease symptoms and risk factors, pharmacologic sensitivity, and pharmacokinetics of many drugs . As more continues to be learned aboutchronobiology and chronotherapeutics, it is becoming increasingly more evident that the specific time that patients take their medication may be even more significant than was recognized in the past. The tradition of prescribing medication at evenly spaced time intervals throughout the day, in an attempt to maintain constant drug levels throughout a 24-hour period, may be changing as researchers' report that somemedications may work better if their administration is coordinated with day-night patterns and biological rhythms.
An overview of the global market bioavailabilty of drugs, including coverage of therapeutics such as antibacterials, antidepressants, anticancer agents, anti-arthritics, cardiovascular drugs sector is expected to reach $300.9 billion in 2013 and $518.5 billion in 2018, with a compound annual growth rate (CAGR) of 11.5%.
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