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Bacteriocins are proteinaceous toxins produced by bacteria to inhibit the growth of similar or closely related bacterial strain(s). They are phenomenologically analogous to yeast and paramecium killing factors, and are structurally, functionally, and ecologically diverse. Applications of bacteriocins are being tested to assess their application as narrow-spectrum antibiotics. Microbial selection of polyphosphate-accumulating bacteria in activated sludge wastewater treatment processes for enhanced biological phosphate removal. Microbial metabolism is the means by which a microbe obtains the energy and nutrients (e.g. carbon) it needs to live and reproduce. Enzymology is the branch of biology that deals with the chemistry, biochemistry, and effects of enzymes. Screening allows the discarding of many valueless microorganisms, at the same time it allows the easy detection of the useful microorganisms that are present in the population in very less number. Microbial Biochemistry covers the principles and importance of microbes, their growth as well as their effects on our environment at large and human health in particular.
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Scope and Importance:
Bacteriocins are an abundant class of antimicrobial molecules that appear to mediate population dynamics within species. The bacteriocins of Escherichia coli have served as a model for exploring the ecological role of these potent toxins. Studies suggest that colicins provide a competitive edge in nutrient-poor environments and that there might be a trade-off between the costs and benefits of colicin production.
Bacteriocins are proteinaceous toxins produced by bacteria to inhibit the growth of similar or closely related bacterial strain(s). They are typically considered to be narrow spectrum antibiotics, though this has been debated. They are phenomenally analogous to yeast and paramecium killing factors, and are structurally, functionally, and ecologically diverse. Bacteriocins are of interest in medicine because they are made by non-pathogenic bacteria that normally colonize the human body. Loss of these harmless bacteria following antibiotic use may allow opportunistic pathogenic bacteria to invade the human body. Bacteriocins can target individual bacterial species, or provide broad-spectrum killing of many microbes. As with today's antibiotics, bacteria can evolve to resist bacteriocins. However, they can be bioengineered to regain their effectiveness. Further, they could be produced in the body by intentionally introduced beneficial bacteria, as some probiotics do.
Relevant Society and Associations
Armenian Microbiological Association
Austrian Society for Hygiene, Microbiology and Preventive Medicine
Belgian Society for Microbiology
Bulgarian Society for Microbiology (Union of Scientists in Bulgaria)
Microbiology Society of BiH
Belarussian Non-governmental Association of Microbiologists
Swiss Society for Microbiology
Czechoslovak Society for Microbiology
German Society of Hygiene and Microbiology
Association for General and Applied Microbiology
Danish Microbiological Society
Estonian Society for Microbiology
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This page was last updated on 14th Sep, 2015
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