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The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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Scope and Importance:
Many of the future challenges of pathogenomics begin with handling and making sense of the large influx of data that now is available to the research community. Mining the data for useful information proves to be applicable to many facets of epidemiology. Bioinformatics approaches are providing much of the power for rapidly mining, organising, analyzing, visualizing and annotating the data catalogued in databases.
Pathogenomics is the field of science which focuses on the molecular interaction between plants and pathogens. Use is made of the latest omics technologies to help identify genes which confer resistance or indeed, susceptibility, of a plant to a particular pathogen. Furthermore, determining the molecular mechanisms behind the plant / pathogen interaction is a key to developing new strategies for enhancing resistance to important pathogens in crop plants. An important aspect of pathogenomics is that research is two - sided, where the both the genetics of the plant and the pathogen are targets of investigation. The CBSG pathogenomics programme covers research on both potato and tomato but due to the advantages of speed and versatility, much research on the molecular basis of plant-pathogen interaction is focused on arabidopsis.
The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes. Through work on this model plant we aim to home in more rapidly on genes linked to disease and thus arrive earlier at novel strategies for crop protection.
The market for pathogenomics is expected to grow at a significant rate. Global Market is expected to reach USD 2.56 Billion by 2022. Constant technological advancements pertaining to the development of pathogenomics which is used to boost usage rates over the forecast period.
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