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As per available reports about 2 relevant journals, 490 Conferences/workshops and 17 Symposiums are presently dedicated exclusively to Growth factor and about 105 articles are being published on Growth factor.
Growth factors are group of proteins, which play an important role in the stimulation of cellular differentiation and cell division. Growth factors are proteins that can function as growth stimulators (mitogens) and/or growth inhibitors, stimulate cell migration, act as chemotactic agents, inhibit cell migration, inhibit invasion of tumor cells, modulate differentiated functions of cells, involved in apoptosis, involved in angiogenesis and promote survival of cells without influencing growth and differentiation.
Examples for Growth Factors are EGF, FGF, NGF, PDGF, VEGF, IGF, GMCSF, GCSF, TGF, Erythropieitn, TPO, BMP, HGF, GDF, Neurotrophins, MSF, SGF, GDF and more.
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Growth factor, any of a group of proteins that stimulate the growth of specific tissues. Growth factors play an important role in promoting cellular differentiation and cell division, and they occur in a wide range of organisms, including insects, amphibians, humans, and plants.
There are different kinds of growth factors, many of which were originally isolated from the tissues of animals, including mice and cattle. Examples of these substances include insulin-like growth factors (somatomedins), epidermal growth factor, platelet-derived growth factor and nerve growth factor. A growth factor that is ubiquitously distributed in plants, animals, and microorganisms is lipoic acid, which is used in photosynthesis and lipid and carbohydrate metabolism. Some cytokines, small proteins released by one cell to regulate the function of another cell, can act as growth factors.
Several growth factors are used therapeutically. For example, erythropoietin, which stimulates the growth of red blood cells, is used to treat anemia associated with chronic kidney failure, cancer chemotherapy, and zidovudine (AZT) therapy in AIDS patients. Granulocyte colony-stimulating factor (G-CSF; filgrastim) and granulocyte-macrophage colony-stimulating factor (GM-CSF; sargramostim) are used to stimulate the production of white blood cells in patients with cancer. These agents also can be used to mobilize hematopoietic progenitor cells (hematopoietic stem cells) into the peripheral blood circulation in order to generate cells that can be harvested and used for autologous bone marrow transplant.
The abnormal production and regulation of growth factors can play a role in the progression of disease. For example, vascular endothelial growth factor induces endothelial cells (the building blocks of capillaries) to penetrate a tumour nodule and begin the process of angiogenesis, or capillary growth—a hallmark in the progression of cancer.
Growth factors are mainly used in the treatment of chronic diseases, such as anemia, renal disorders, cancer, etc. For instance, erythropoietin, which stimulates the growth of Red Blood Cells (RBCs), is used to treat anemia. Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) and Granulocyte Colony-Stimulating Factor (G-CSF) are involved in the stimulation of White Blood Cells (WBCs) in cancer patients. The global growth factors market covers various blood growth factors and tissue growth factors. Blood growth factors include colony stimulating factors, erythropoietins, interferons and interleukins.
In terms of geography, North America dominates the global growth factors market. This is due to improved health care infrastructure and increasing prevalence of chronic diseases in the region. In addition, growing demand for recombinant growth factors has also propelled the growth of the market in North America. The U.S. represents the largest market for growth factors in North America, followed by Canada. In Europe, Germany, France, and the UK. account for the major share of the growth factors market. The growth factors market in Asia is also expected to expand at a higher rate in the next five years. This is due to the rising awareness about therapeutic applications of growth factors in the treatment of chronic diseases in the region. In addition, increasing prevalence of chronic diseases and growing aging population are driving the expansion of the growth factors market in the region. Growing demographics and economies in developing countries, such as India and China, are expected to lead to the rise in the growth factors market in Asia. Moreover, India, China and Japan are expected to be the fastest growing markets for growth factors in the region.
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This page was last updated on 09th Sep, 2015
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