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Recommended Conferences for Mimogen-a

Mimogen-a


As per available reports about 2 relevant journals, 1 Conferences, 1 workshops are presently dedicated exclusively to Mimogen-a and about 2,070 articles are being published on Mimogen-a. 

Therapeutic vaccine is a potentially promising means for the treatment of chronic hepatitis B in clinic, yet no is available at present. εPA44 is a de novo designed mimogen that acts as a tri-epitope integrated immunogen in order to prime therapeutic immunity while avoiding harmful and unnecessary immunity. To prove the mimogen concept, we performed a randomized, dose–escalation trial in 56 normal healthy research volunteers and a randomized, double–blind, placebo–controlled trial in 46 patients in two centers in China

Although mass inoculation with preventive vaccines have drastically decreased the prevalence of hepatitis B virus (HBV)infection in a few countries, the pool of post-exposure population worldwide remains essentially unchanged. Therapeutic vaccine is a potentially promising means for the treatment of chronic hepatitis B in clinic, yet no is available at present. εPA44 is a de novo designed mimogen that acts as a tri-epitope integrated immunogen in order to prime therapeutic immunity while avoiding harmful and unnecessary immunity. To prove the mimogen concept, we performed a randomized, dose–escalation trial in 56 normal healthy research volunteers and a randomized, double–blind, placebo–controlled trial in 46 patients in two centers in China. εPA44 was well tolerated and safe in all participants, and induced designed immune responses that included vigorous HBV-specific CTLs, anti-Pre-S(2) antibodies, Th1 cytokines, and downregulated regulatory T cells. εPA44 might also decrease serum viral load of HBV and conduce serum HBeAg/HBeAb seroconversion in patients, which could persist to week 252 without relapse. Our findings highlight the potential of mimogen strategy for treating patients with chronic infections.
 

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Conferences :

Socities :
• American Society for Microbiology
• Society for Applied Microbiology- UK
• International Union of Microbiological Societies
• Society for General Microbiology Journals
• American Society for Microbiology Career Connections
• The Canadian Society of Microbiologists
• European Microbiological Society.
• Illinois Society of Microbiology
• British Society for Microbial Technology
• New Zealand Microbological Society

Companies:
• Pfizer
• Novartis
• Roche
• Merck & Co.
• Sanofi
• GlaxoSmithKline
• Johnson & Johnson
• AstraZeneca
• Lilly
• AbbVie

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This page was last updated on March 28, 2024

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