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ANANBIOANAL - 2010
Pharmaceutical R & D Summit
doi:10.4172/2155-9872.1000087
Nano-Structured and Atomic Cluster Materials in Trace and
Ultratrace Analysis of Bio- and Envirotoxic Markers
T. Prasada Rao
Scientist G, Chemical Sciences & Technology Division, National Institute for Interdisciplinary Science & Technology (NIIST)-CSIR,
Trivandrum, India.
T
he selection of appropriate analytical technique for detection and quantification
of ultra trace amounts of bio- and envirotoxic markers depends on primary
criteria such as sensitivity, selectivity, precision and accuracy in addition to auxiliary
criteria like availability, cost of equipment, time of analysis, sampling and standards
requirements. Various singular and hyphenated techniques have been developed
over the years which include spectral, electrochemical, radiochemical, X-ray and
mass spectrometric. In spite of such significant advances in analytical instrumentation,
analytical chemists often resort to either off-line or on-line pre-concentration to
reliably quantify bio- and envirotoxic markers present in complex matrix and several
other analogous co-existing species.The invited talk consists of 2 parts namely gold
atomic clusters and nano-structured molecularly imprinted polymer materials for
ultra trace detection and quantification of biomarkers(Cysteine and Tyrosine) and
envirotoxic markers(Uranium). In addition, the electrocatalytic red-ox behaviour of
atomic cluster scaffolds and functional nano-material modified gold/glassy carbon
electrodes will be described. Furthermore, the synthesis and characterization of
surface imprinted nano-spheres for pre-concentrative separation of uranium and
successful utilization of these materials for harnessing or decontamination of
uranium from various natural water simulants including SAMBHAR SALT LAKE will
be touched upon.
ANALBIOANAL-2010
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