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ANANBIOANAL - 2010
Doxorubicin
Jyoutsna Anand*, Devendra Phatak
Rajiv Academy for Pharmacy, Delhi - Mathura highway, Mathura
D
for the assay of doxorubicin. The method used a column C18
oxorubicin is the one of the most potent antitumor drug of Bone Cancer, Breast
cancer. A simple and sensitive HPLC method was developed and validated
(250mm*4.6mm)
with a UV. Detector is 254nm wavelength. The mobile phase consists of buffer
solution (Sodium Lauryl Sulphate & OrthoPhosphoric Acid): Acetonitrile. Flow rate
was found 1.0ml/min. All the system suitability parameter was found according to
the ICH standards. The method was extensively validated for specificity, linearity,
accuracy and precision, recovery robustness. The present assay of drugs was
found to be in range.
Pharmaceutical R & D Summit
doi:10.4172/2155-9872.1000043
Method Development and Validation of Anti-cancer Drug:
ANALBIOANAL-2010
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