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ANANBIOANAL - 2010
Pharmaceutical R & D Summit
doi:10.4172/2155-9872.1000003
Combined Laser Induced Breakdown Spectroscopy and Raman
Spectroscopy for Pharmaceutical Applications
G Manoj Kumar
Advanced Centre of Research in High Energy Materials (ACRHEM)
University of Hyderabad, Hyderabad, India
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will talk about two complementary spectroscopic techniques, namely Laser
Induced Breakdown Spectroscopy (LIBS) and Raman Spectroscopy for the
pharmaceutical applications. While Raman spectroscopy which is widely used in
the industry to get the molecular information, LIBS is a relatively new technique
that gives atomic information. It is an atomic emission based technique involving
the interaction of a target with an intense laser pulse which generates plasma.
The spectral analysis of the fluorescence emission from the cooling plasma plume
contains specific signature of atoms of the material under investigation. The amount
of sample and time needed to prepare the sample are far less compared to any
other technique used for the elemental analysis such as Absorption, Fluorescence,
FT-IR, Raman or Cavity Ring down Spectroscopy. LIBS is particularly attractive for
the detection due to its stand-off detection capability, requirement of microscopic
quantities of material, and rapid detection. The detection times are very fast which
is very ideally suited for the industrial applications. LIBS and Raman studies on
pharmaceutical samples have been reported in a recent study. A combined system
capable of recording both the Raman and the LIBS spectra can give complementary
information.
ANALBIOANAL-2010
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