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International Conference on Retroviruses and Novel Drugs
June 08-09, 2015 Chicago, Illinois, USA
 

Theme: Current Concepts In Retroviruses & Advanced Drug Researches

The International Conference on Retroviruses and Novel Drugs to be held at Chicago, USA during June 08-09, 2015 hosted by OMICS Group Conferences through the theme "Current concepts in Retroviruses & Advanced drug researches", conference will explore the advances in Drug researches by Clinical virologists, Pharmacologists etc.. This conference could be an exceptional event that brings along a novel and International mixture of giant and medium antiretroviral analysis, leading universities and novel drugs analysis establishments creating the conference an ideal platform to share expertise, foster collaborations across trade and world, and assess rising technologies across the world. OMICS International Publishes 400+ Open access journals which contains over 30000 eminent personalities, reputed scientists as editorial board members and Organizes 300+ Conferences every year across USA, Europe & Asia with support from 1000 more scientific societies.

Retroviruses is a root cause to understand the mechanism of a disease. It is a subject for the professionals who looks beyond the clinical expectations. Retroviruses -2015 gathers all the extroverts under one roof of current advances.

 

For more details please visit- http://retrovirus.conferenceseries.com/index.php

Importance & Scope:

   Chicago is the third most populous city in both the United States of Illinois and the American Midwest. Its metropolitan area, sometimes called Chicagoland, is home to 9.5 million people and is the third-largest in the United States. OMICS International Conference is a great platform in Chicago for the researchers to explore knowledge and get new ideas to fight against these diseases and infections. A retrovirus is a virus that uses RNA as its genetic material. When a retrovirus infects a cell, it makes a DNA copy of its genome that is inserted into the DNA of the host cell. There are a variety of different retroviruses that cause human diseases, including the common cold, some forms of cancer, and AIDS. The World Health Organization (WHO) has reported that the prevalence of HIV drug resistance has been around 7% between the years 2003 and 2010 worldwide. With the expansion of ART coverage achieved over the last years, increasing prevalence of HIV drug resistance has been reported, particularly to Non-Nucleaoside Reverse Transcriptase Inhibitors (NNRTI) . Reports suggest that 10-17% of naïve HIV patients in Australia, Japan, United States and Europe are infected with resistant viral strains to at least one of the ART agents. At the end of 2008, an estimated 1,178,350 persons aged ≥13 years were living with HIV infection, including 236,400 (20.1%) whose infections had not been diagnosed in united states . There are six major universities in chicago they are University of chicago, Loyola University Chicago, Harvard University , Cornell University, Institute of Human Virology, Centre for Human Virology. whose research interest range from the retrovirus-host interactions, including the anti-virus immune response and the genetics of resistance to retroviral infection and to virally induced tumors. Investigation of mechanisms of resistance to retroviral infections in murine models. Thesis research on the mechanism of retroviral resistance inherited by I/LnJ mice. And also Understanding basic molecular functioning of these retroviruses with a view to develop new antiretroviral drugs. Major Companies like Cipla, Zidovudine, Hetero Drugs,  Emcure Pharmaceuticals, Protease inhibitor, Quality Chemical Industries Limited, Ranbaxy in United States respectively manufacturing antiretroviral drugs which is used to cure the retroviral diseases worldwide.

Why in Chicago ?

      Depending on the Compound annual growth rate of retrovirus market America stands in first rank next comes European countries and Asia. So the Retroviruses-2015 in going to be held in America

Metropolitan  Chicago is a major regional hub for the health care industry and boasts a small, globally competitive manufacturing sector. Chicago is having 6 major universities, 9 societies which are working on the field. USA is having 7 major companies which are producing antiretroviral drugs.

Figure 1: Antiretroviral Drug Market by Geography Reference 1

 

Conference Highlights:

  • Early Evolution
  • Retroviral Diseases
  • Retroviral Infections
  • Viral Pathogenesis
  • Endogenous Retrovirus
  • Viral Immunology And Mechanism
  • Gene Therapy
  • Cancer Virology
  • HIV Host Interactions
  • Current HIV Researches and Treatment

 Why to attend???

Retroviruses-2015 could be an exceptional event that brings along a novel and International mixture of giant and medium virology analysis, leading universities and Companies establishments creating the conference an ideal platform to share expertise, foster collaborations across trade and world, and assess rising technologies across the world. World-renowned speakers, the most recent techniques, tactics, and the newest updates in the field of Retroviruses and Novel Drugs are hallmarks of this conference.

A Unique Opportunity for Advertisers and Sponsors at this International event:

http://retrovirus.conferenceseries.com/sponsors.php

 

Major virology Associations in & around Chicago

  • Association of Adherence to Mycobacterium avium Complex Prophylaxis and Antiretroviral Therapy with Clinical Outcomes in Acquired Immunodeficiency Syndrome
  • International Retrovirology Association
  • American Medical Association Chicago
  • Association of Human Endogenous Retroviruses with Multiple Sclerosis
  • Association of Immune Activation
  • American Urological Association
  • American Association for Cancer Research.
  • American Association for the Advancement of Slavic Studies
  • International Association of Physicians in AIDS Care

 

Major Retroviral Associations in USA

  • Human Endogenous Retrovirus HERV-Fc1 Association
  • Registered Facilities - Association of Academic Biologics
  • American Association of Feline Practitioners (AAFP)1
  • Association of RON tyrosine kinase with the Jaagsiekte
  • Association of the Human Type C Retrovirus
  • A new human retrovirus associated with prostate cancer
  • Association of endogenous retroviruses
  • association of recombinant GPI proteins to retroviral
  • American Association of Feline Practitioners' feline retrovirus
  • American Association for the Advancement of Science
  • American Association for Cancer Research
  • AIDS Treatment News (ATN)

Figure 2: Retroviral Associations and societies in number Source -  2  3 4

Target Audience:

Practicing virologists, scientists in training and other healthcare professionals interested in the latest advances drug researches in the field. Another segment of target audience is Pharmaceutical researchers, Clinical organizations, Educational institutes. Senior scientists, Pharma Industries etc.,

 

Total Virologists

  • Chicago- 680
  • USA - 15000
  • World Wide- 150000

Figure 3: Number of Virologists

Source: 5  6  7  8  9  10  11  12

Virology Associated Universities

In and Nearby Chicago

  • University Of Chicago
  • Loyola University Chicago
  • Harvard University
  • Cornell University
  • Institute of Human Virology
  • Centre for Human Virology

Top Universities USA

  • The Department of Molecular Virology and Microbiology
  • The Institute of Human Virology
  • Institute of Molecular Virology at Saint Louis University School of Medicine.
  • The Department of Molecular Virology, Immunology, and Medical Genetics
  • The Department of Virology and Immunology at the Southwest Foundation for Medical Research, in San Antonio, Texas.
  • The Pittsburgh Bacteriophage Institute
  • National Cancer Institute's HIV Drug Resistance Program –
  • The Gladstone Institute of Virology and Immunology at San Francisco General Hospital, with faculty from the University of California San Francisco.
  • Center for Complex Infectious Diseases (CCID) -
  • Institute for Molecular Virology at the University of Wisconsin-Madison
  • The Irvine Research Unit in Animal Virology
  • The U.S. Army Medical Research Institute of Infectious Diseases –
  • Southern Research Institute's Infectious Disease Research Department,

 

Figure 4: Universities in Number Source- 13 14

Companies Associated with Retroviral drugs

  • Cipla
  • Zidovudine
  • Hetero Drugs  
  • Emcure Pharmaceuticals
  • Protease inhibitor
  • Quality Chemical Industries Limited
  • Ranbaxy

Hospitals & Laboratories Associated with Retrovirus

In  Chicago

  • Northwestern Memorial Hospital
  • All Women's Health Chicago
  • West Loop STD Treatment Clinic
  • West Town STI Specialty Clinic
  • Oak Lawn Immediate Care
  • Roseland  STI Specialty Clinic
  • Lawndale Christian Health Center
  • Illinois HealthCare Clinic

World Wide

  • Lenox Hill Hospital Retroviral Disease Center
  • Care of Patients on Anti-Retroviral Therapy
  • Antiretroviral HIV and AIDS treatment provision
  • AIDS Treatment - UCSF Medical Center
  • The anti-retroviral (ARV) treatment programme
  • Predictors of mortality among HIV infected children
  • Snehalaya | Community Care Center
  • Berlin's Charité Hospital
  • Uppsala University Hospital
  • Emory University Hospital

Top Independent Commercial Retroviral Labs

  • ADGEN Ltd
  • Aldna Diagnostics
  • Almen Labs 
  • Amersham
  • Antec International 
  • Antex Biologics
  • Arpex Biosciences          
  • Sekot Laboratories
  • Virologix Corporation

The following are some of the retrovirology Kits & software’s produce by the companies

Retrovirus Kits

  • Ancillaries for IHC Retrovirus Packaging Kits (Takara)
  • Rapid Lentiviral and Retroviral Titration Kits
  • (MRVI1) ELISA Kit
  • Retrovirus Purification Mini Kit
  • Retrovirus iPS Cell Reprogramming Kit
  • Retrovirus Concentration and Purification Kits
  • ARGENT™ Regulated Transcription Retrovirus Kit
  • Retroviral Expression Systems

Retroviral Software’s

  • RTCGD: retroviral tagged cancer gene database
  • HERVd: database of human endogenous retroviruses
  • ERE database
  • GPS  

Market Analysis of Retrovirology

The overall Canadian market is expected to experience on-going challenges and uncertainties until 2014 which will weigh on corporate performances. Conditions in the industry are expected to be brighter in the 2014-2016 period with annual forecasted growth ranging from 3% to 5%, doubling the sluggish growth forecast for 2012 and 2013. The compound average annual growth forecast for the 2012-2016 period is 2.8% with the brand and generic segments anticipated to grow at a similar pace.Footnote50 While this projected growth rate is encouraging compared to the last several years, Canada‘s growth will continue to lag those of emerging markets.

 Market growth in Canada and in developed markets will continue to be outpaced by fast growing emerging markets (see Figure 8). China and Brazil, the largest emerging markets are anticipated to grow 13% and 17% annually in the medium term. Emerging markets will drive overall global expansion and they will continue to gain sales volume and market share. The value of the global market is forecasted to reach the $1 trillion in 2014.

Figure 6:  Market analysis Source - 15

International Funding for HIV

Figure 7: International funding on HIV Source - 16

 

Prevention and control:

The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs in an attempt to control HIV infection. There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of multiple drugs that act on different viral targets is known as highly active antiretroviral therapy (HAART). HAART decreases the patient's total burden of HIV, maintains function of the immune system, and prevents opportunistic infections that often lead to death. Increased risk of contracting HIV often correlates with infection by other diseases, particularly other sexually transmitted infections. Medical professionals and scientists recommend treatment or prevention of other infections such as herpes, hepatitis A, hepatitis B, hepatitis C, human papillomavirus, syphilis, gonorrhea, and tuberculosis as an indirect way to prevent the spread of HIV infection. Often doctors treat these conditions with pharmaceutical interventions Programs encouraging sexual abstinence do not appear to effect subsequent HIV risk. Evidence for a benefit from peer education is equally poor. Comprehensive sexual education provided at school may decrease high risk behavior. A substantial minority of young people continue to engage in high-risk practices despite HIV/AIDS knowledge, underestimating their own risk of becoming infected with HIV. It is not known if treating other sexually transmitted infections is effective in preventing HIV. Early treatment of HIV-infected people with antiretrovirals protected 96% of partners from infection. Pre-exposure prophylaxis with a daily dose of the medications tenofovir with or without emtricitabine is effective in a number of groups including: men who have sex with men, by couples where one is HIV positive, and by young heterosexuals in Africa.The retroviral diseases can controlled by acute retroviral syndrome

 

Current Researches:

  • Molecular Mechanisms of Viral Pathogenesis
  • Antiviral Targets and Strategies
  • Retroviral Pathogenesis
  • Antiretroviral Drug Discovery & Development
  • Novel Therapeutic Approaches
  • Retroviral Infections
  • Viral Immunology and Mechanism

Future aspects:

  • Retroviral Vectors for Gene Therapy
  • Human retroviruses after 20 years: a perspective from the past and prospects for their future control.
  • Retroviral insertional mutagenesis: past, present and future.
  • Koala Retrovirus Workshop conclusion. The future of KoRV research—foundational and applied
  • Side effects of retroviral gene transfer into hematopoietic stem cells
  • Retroviruses, engineering and the future of science
  • Retrovirus Infections of the Nervous System: Current and Future Perspectives

References:

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