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The term “planter” this means plants & “some” which means similar to cell. Planterosomes are novel forms similar to cell. Planterosomes are novel forms which, through the skin, offer enhanced bioavailability of hydrophilic flavonoids & other compounds which are similar to them. Planterosomes are often known as phytosomes or herbosomes when compared to conventional herbal extracts, planterosomes exhibit better pharmacokinetic and pharmacodynamics profile.
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It enhances the absorption of lipid insoluble polar phytoconstituents through oral as well as topical route showing better bioavailability, hence significantly greater therapeutic benefit Appreciable drug entrapment. As the absorption of active constituent(s) is improved, its dose requirement is also reduced. Phosphatidylcholine used in preparation of planterosomes, besides acting as a carrier also acts as a hepatoprotective, hence giving the synergistic effect when hepatoprotective substances are employed. Chemical bonds are formed between phosphatidylcholine molecule and phytoconstituent, so the planterosomes show better stability profile. Application of phytoconstituents in form of planterosome improves their percutaneous absorption and act as functional cosmetics.
Planterosome is complex between dietary phospholipids and polar polyphenolics. It shows spectroscopic and physicochemical features. New avenues open up when recent technology of drug delivery are applied to botanicals exploring maximum therapeutic potential of plant substances that are potential in nature. Chemical bonds are formed between phosphatidylcholine molecule and phytoconstituent, so the planterosomes show better stability profile. Application of phytoconstituents in form of planterosome improves their percutaneous absorption and act as functional cosmetics. Application of phytoconstituents in form of planterosome improves their percutaneous absorption and act as functional cosmetics. Planterosomal complexes were investigated for cosmetic applications in the beginning, but over the past few years evidences have shown that it has paramount potential for drug delivery and can be applied with beneficial activity as a hepatoprotective, anti-inflammatory, cardiovascular and anti-cancer drug.
The sales of planterosomes combination products reached $21.4 billion in 2013 and $22 billion in 2014. This market is expected to grow to $31 billion in 2019, with a compound annual growth rate (CAGR) of 7.1% from 2014 to 2019. An overview of the global market for drug-device combinations. Analyses of global market trends, with data from 2013 and 2014, and projections of CAGRs through 2019. Detailed coverage of such product categories as drug-eluting stents (DES), drug-eluting beads (DEB), antimicrobial catheters, antibiotic-loaded bone cements, glass ionomer cements, bone graft substitutes, antibacterial-releasing dental restorative materials, biologic wound care products such as collagen-based dressings as therapeutic agents for wound healing, drug-device combination products for ocular applications, and photodynamic therapy.
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