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As per available reports about 10 relevant journals, 15 Conferences, 30 workshops are presently dedicated exclusively to Microbail Factories and about 2,070 articles are being published on Microbial Factories.
Microbial productions have occupied a significant role in various areas like fermentation industry, food and beverage industry, biotechnology research, detergent industry. Microbial productions have pivotal responsibility in industrial biotechnology which involves the use of microorganisms and enzymes to produce bio based products in sectors like chemicals, food & feed, paper, textiles and bio energy. Microbial products include antibiotics, enzymes, vitamins, amino acids. Antibiotics are substances derived by some bacteria or fungi that can either inhibit the growth or kill other microorganisms. Antibiotics are produced industrially by fermentation where the source microorganism is grown in containers of size 100,000–150,000 litters or more in the presence of liquid growth medium.
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Microalgae as a biofactory offer a promising approach towards the production of omega-3 fatty acids such as eicosapentaenoic acid (EPA) and docosaheaenoic acid (DHA). These fatty acids provide significant health benefits and their consumption has increased as dietary supplements. Microalgal biotechnology explores the potential applications of autotrophic microalgae as aquaculture feed and in the development of biofuel crops. Microalgae can also be used as the production platforms for the development of omega- 3 fatty acids. Studies have reported that techniques like metabolic engineering and selective breeding can be applied successfully to produce large amounts of omega-3 fatty acids in microalgeas.
Microbial cells, either bacteria or yeast are used as hosts to produce recombinant pharmaceuticals. Food and Drug Administration (FDA) and the European Medicines Agency (EMEA) have represented that the microbial cells represent convenient and powerful tools for recombinant protein production. Biofactory refers to any system that can produce useful amounts of biologically-active compounds such as recombinant proteins, therapeutics. Hosts such as bacteria, yeasts, mammalian and insect cells, transgenic plants and animals can be exploited for the large-scale production of diagnostic and therapeutic proteins. Molecular farming which is a keystone tool of plant biotechnology focuses on the exploitation of plants of agronomic relevance as bio factories for large scale production of bio molecules. The whole plant or plant cell culture have been used for the production of biopharmaceuticals like cytokines, blood proteins, milk proteins, hormones, antibodies, metabolic enzymes, antigens and vaccines and many more biological molecules used in animal and human health care.
The major product class of fermentation chemicals consists of alcohols, enzymes and organic acids. Fermentation chemicals are utilized in variety of applications in a wide range of chemical processes in industries such as alcohol industry, pharmaceutical industry, food and beverages industry, chemical industry, textile industry and rubber industry among others. The revenue generated by the global fermentation chemicals market was USD 41,567.7 million in 2012 which is expected to reach USD 60,123.9 million by 2019, growing at a CAGR of 5.4% from 2013 to 2019.
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This page was last updated on 12th Sep, 2015
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