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In Vitro Toxicity


As per available reports about 18 Conferences, 2 Workshops and 9 Relevant journals are presently dedicated exclusively to In Vitro Toxicity and about 200 articles are being published on In Vitro Toxicity.

The scientific analysis of the effects caused by toxic substances on cultured bacteria or any other mammalian cells is termed as In vitro toxicity testing. It is used for identification of toxicants and also to analyse the extent of efficacy and safety of new substances such as medicines, preservatives, pesticides etc. This is usually done by performing different assays.  This method is one of the best alternative for animal testing.

OMICS International Organizes 1000+ Global Events Every Year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open access journals which contains over 100000 eminent personalities, reputed scientists as editorial board and organizing committee members. The conference series website will provide you list and details about the conference organize worldwide..

OMICS International Conference series focuses to enhance knowledge dissemination among its varied range of participants including eminent speakers, renowned scientists, industrialists from top notch companies, young researchers and students. OMICS International Pharma conferences foster the better understanding of latest scientific researches by providing a global exposure to its participants where they can associate with relatable professionals. The scope of these gatherings is  further extended by encompassing remarking key areas like Pharmaceutical Regulatory Affairs, Mass Spectrometry, Separation Techniques, Toxicology , Therapeutic Drug Monitoring and Toxicogenomics, Pain Medicine, Clinical Pharmacy, GMP and GLP quality control, followed by Bioavailability and Bioequivalence studies, Biosimilars and Pharmacognosy.

Scope and Importance:

To identify potentially hazardous chemicals and/or to confirm the lack of certain toxic properties in the early stages of the development of potentially useful new substances such as therapeutic drugs, agricultural chemicals and food additives In vitro (literally 'in glass') testing methods are employed. In vitro methods are routinely used by all industries and regulatory bodies in toxicity testing, safety assessment, and risk evaluation, and offer unique advantages. The greatest use of in vitro methods, however, is for elucidating mechanisms of toxicity and/or demonstrating the biological process involved in a toxic response to a xenobiotic, including drugs. With the development and widespread use of the Ames Mutagenic Assay, non-animal testing became routine in both industry and regulatory laboratories.

In both U.S. and European laboratories, scientists have vigorously pursued the development of in vitro methods to advance their science. During the last 20 years, the considerable and significant advances in tissue culture methodology, the use of chemically-defined cell and tissue culture media, and the availability of human cells have transformed in vitro methods from a new technology to a valuable research tool. The concept of refinement,reduction, and replacement became known as the Three Rs, and methods which incorporated one or more of the Three Rs were considered "alternative" methods.

Numerous centers throughout the world that focus on the development, validation, and use of alternatives in the biomedical sciences (including toxicology). As the science behind in vitro technology advances, and as results from new methods are shown to be both transferable and reproducible, these alternatives continue to gain acceptance. Additionally, the scientific community has responded to the substantial public outcry for a decrease in animal use by considering the advantages and limitations of alternatives.

OMICS International is planning to conduct the conference on in vitro toxicity. The conference in vitro toxicity brings together Scientists, researchers, Corporate Managers, Academicians, Decision Makers from the Pharma, Biotech and Health Care industries, Lab Directors and other experts involved in the field of Toxicology to discuss with the advances in hazard identification and risk assessment and the conference aims to address important issues facing the various chemical industries, including regulatory requirements; the reduction, refinement, and replacement of animal testing; new screening methods; evaluation of new cell and tissue models; and the most appropriate methods for assessing safety and satisfying regulatory demands.

Market Analysis:

In 2011 the global in vitro toxicity testing market was valued at $4 billion and more than $4.9 billion in 2012. In 2017 this is estimated to reach nearly $9.9, with a compound annual growth rate (CAGR) of 14.7% for the five-year period, 2012 to 2017.

The global in vitro toxicity (predictive toxicity) testing market is valued at more than $1.3 billion in 2010.  Due to increased awareness of animal welfare in laboratory research testing, the in vitro toxicity testing market has an anticipated value of $2.7 billion in 2015, a compound annual growth rate (CAGR) of 15% between 2010 and 2015.

Cosmetics and personal-care industry accounts for more than 50% of the market share is accounted This sector is currently valued at $702 million and is expected to reach $1.3 billion by 2015, a compound annual growth rate (CAGR) of 13.1%.

The pharmaceuticals segment is one of the most significant with a 32% market share valued at $424 million in 2010. By 2015, this sector is projected to reach a value of $976 million, a compound annual growth rate (CAGR) of 18.2%.

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Related Societies:

  1. in vitro toxicology Society
  2. The European Society of Toxicology In Vitro (ESTIV)
  3. In Vitro Toxicology Society (IVTS)
  4. European Consensus-Platform for Alternatives
  5. National Centre for the Replacement, Refinement and Reduction of Animals in Research
  6. ZEBET - Centre for Documentation and Evaluation of Alternatives to Animal Experiments
  7. Center for Alternatives to Animal Testing (CAAT)

Related Companies:

  1. Myriad RBM, Inc.
  2. Cyprotex
  3. Pacific BioLabs
  4. Gentronix
  5. BioAntares LLC
  6. Bio Développement
  7. PreKlin Research Labs
  8. Xenometrix
  9. Biocroí
  10. Stratagene
  11. Geneva Laboratories, Inc.

This page will be updated regularly.

This page was last updated on 15th Sep, 2015

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