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Adipocytes, also known as lipocytes and fat cells, are the cells that primarily compose adipose tissue, specialized in storing energy as fat. There are two types of adipose tissue, white adipose tissue (WAT) and brown adipose tissue (BAT), which are also known as white fat and brown fat, respectively, and comprise two types of fat cells Brown fat cells or plurivacuolar cells are polygonal in shape. Unlike white fat cells, these cells have considerable cytoplasm, with lipid droplets scattered throughout.
As adults, obese people do not have more fat cells than thin people, but their fat cells are larger. The same is true in reverse: When an obese or overweight person loses weight, the fat cells shrink. But the number of fat cells doesn't change, just their size. Large fat cells have been linked to some of the chronic health conditions related to obesity, such as diabetes. Because of physical problems like improper functioning of Endocrine system such as thyroid disorders obesity occurs. There are many health risks associated with obesity, controlling obesity helps in developing high nutrition values and healthy life style.
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Scope and Importance:
Adipocytes were considered to be little more than storage cells for fat. What we now know, however, is that adipocytes are a critical component of metabolic control and endocrine organs that have both good and bad effects. This remarkable understanding is allowing us to more clearly define the role adipocytes play in health and in obesity and how inflammatory mediators act as signaling molecules in this process. Moreover, on a molecular level, we are beginning to comprehend how such variables as hormonal control; exercise, food intake, and genetic variation interact and result in a given phenotype.
Adipocytes are critical for health as well as being repositories of free fatty acids (FFAs). Second, adipocytes release hormones that, in lean individuals at least, modulate body fat mass. Third, as a person gets heavier and the adipocytes enlarge, these control mechanisms become dysregulated, macrophages accumulate in the adipose tissue, and inflammation ensues. Finally, the regulators of FFA storage and oxidation in adipocytes and the periphery are critical regulators of metabolic homeostasis.
From 2011 to 2014 there is a sharp increase in total number of adipose cell-based clinical trials worldwide. It jumped more than 3 times (from 11 in 2011 to 40 in 2014). The number of academic-based trials remained flat in the last 3 years. However, there was a big increase in industry-sponsored trials in 2014.
International symposium and workshops:
1. 17th Obesity Conference
May 25 - 26, 2015, London, UK
2. 8th Diabetes & Obesity Riga
July 2-3, 2015, Riga, LATIVIA
3. 8th Biennial Childhood Obesity Conference
June 29- July 2, 2015, San Diego, USA
February 29-March 02, 2016 Philadelphia, USA
2. 5th Childhood Obesity Conference
May 12-14, 2016 Chicago, USA
November 28-30, 2016 San Antonio, USA
September 29-October 1, 2016 Toronto, Canada
August 08-10, 2016 Toronto, Canada
6. 13th Diabetes Conference
August 08-10, 2016 Birmingham, UK
September 14-16, 2015 Las Vegas, Nevada, USA
November 03-05, 2015 Valencia, Spain
June 23-25, 2016 New Orleans, USA
July 11-13, 2016 Brisbane, Australia
11. The XIII Obesity Conference
May 1-4, 2016 Vancouver, BC
12. 8th Diabetes and Obesity Conference
July 2-3, 2015 Riga, Latvia
13. 8th Biennial Childhood Obesity Conference
June 29- July 2, 2015, San Diego, USA
Relevant Society and Associations:
1. European Association for the Study of Obesity
2. Association for the Study of Obesity
3. World Obesity Federation
4. The Obesity Society
5. Association of obesity with anxiety, depression and emotional well-being: a community survey
6. All India Association for Advancing Research in Obesity
7. Associations of obesity with socioeconomic and lifestyle factors in middle-aged and elderly men: European Male Aging Study
8. Stronger associations of obesity with prehypertension and hypertension in young women than in young men
9. Asia Oceania Association for the Study of Obesity
10. International Association for the Study of Obesity
1. Fierce Pharma
3. Arena Pharmaceuticals
5. Orexigen Therapeutics
6. Food and Beverage Marketing
This page will be updated regularly.
This page was last updated on 14th Sep, 2015
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