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As per available reports about 20 relevant journals, 7 Conferences, 6 workshops are presently dedicated exclusively to Electrospray Ionization and about 122 articles are being published on Electrospray Ionization.
The Electrospray Ionization (ESI) is a soft ionization technique extensively used for production of gas phase ions (without fragmentation) of thermally labile large supramolecules. In the present review we have described the development of Electrospray Ionization mass spectrometry (ESI-MS) during the last 25 years in the study of various properties of different types of biological molecules. There have been extensive studies on the mechanism of formation of charged gaseous species by the ESI. Several groups have investigated the origin and implications of the multiple charge states of proteins observed in the ESI-mass spectra of the proteins. The charged analytes produced by ESI can be fragmented by activating them in the gas-phase, and thus tandem mass spectrometry has been developed, which provides very important insights on the structural properties of the molecule. The review will highlight recent developments and emerging directions in this fascinating area of research. One advantage is its ability to handle samples that have large masses. Another advantage is that this ionization method is one of the softest ionization methods available, therefore it has the ability to analyze biological samples that are defined by non-covalent interactions. A quadrupole mass analyzer can also be used for this method, which means that a sample's structure can be determined fairly easily. The m/z ratio range of the quadrupole instrument is fairly small, which means that the mass of the sample can be determined to with a high amount of accuracy.
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Scope and Importance:
The scope of electrospray ionization is impressive and therefore can be useful in accurate quantitative and qualitative measurements. Some disadvantages to electrospray ionization mass spectrometry are present as well. A major disadvantage is that this technique cannot analyze mixtures very well, and when forced to do so, the results are unreliable. The apparatus is also very difficult to clean and has a tendency to become overly contaminated with residues from previous experiments. Finally, the multiple charges that are attached to the molecular ions can make for confusing spectral data. This confusion is further fueled by use of a mixed sample, which is yet another reason why mixtures should be avoided when using an electrospray ionization mass spectrometer.
As per the Frost and Sullivan report analytical market is growing on an average 0.4% annually.This report studies the global electrospray ionization market over the forecast period of 2013 to 2018. The market was estimated at $3.9 billion in 2013 and is expected to reach $5.9 billion by 2018, growing at a CAGR of 8.7% from 2013 to 2018.North America dominated the global electrospray ionization market in 2013, followed by Europe and Asia. The North American market is likely to be driven by factors such as the increasing number of government investments in pharmaceutical, biotechnology, medical, and academic research studies that make use of mass spectrometry techniques. On the other hand, Asia is expected to grow at the highest CAGR due to the presence of high-growth markets such as India and China, the improved funding scenario in this region, increasing number of conferences and exhibitions on mass spectrometry, and increased focus of the giant players in these countries.
International symposium and workshops
1. International Symposium on Standards, Applications and Quality Assurance in Medical Radiation Dosimetry.
2. Proceedings of the Sixth IEEE international conference on Symposium on Biomedical Imaging
3. International Symposium on Digital Industrial Radiology and computed tomography.
4. The SPIE Medical Imaging conference
5. IEEE Nuclear Science Symposium and Medical Imaging Conference
6. Medical Imaging Conferences 2016
List of Best International Conferences:
1. Federation of Analytical Chemistry and Spectroscopy Societies
2. Spectroscopy Society of Pittsburgh
3. Canadian Society for Analytical Sciences and Spectroscopy
4. New York Society for Applied Spectroscopy
5. The Spectroscopical Society of Japan
6. British Mass Spectrometry Society
7. Applied electron spectroscopy for chemical analysis
8. International Council for Near Infrared Spectroscopy
1. Spectroscopic Solutions
2. Specac Limited
3. PIKE Technologies
4. Fluxana GmbH Co. KG
5. Real-Time Analyzers Inc.
6. Guided Wave Inc
7. Tiger Optics LLC
8. Rigaku Raman
9. Harrick Scientific Products Inc
10. Eichrom Technologies
This page will be updated regularly.
This page was last updated on 14th Sep, 2015
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