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Chronic sleep problems affect 50% to 70% of patients in a typical psychiatric practice, compared with 10% to 20% of adults in the general U.S. population. The worst sleep problems are particularly common in patients with anxiety, depression, bipolar disorder, and attention deficit hyperactivity disorder and associated other illness related to sleep. During the night, we move back and forth between quiet sleep and deeper, active sleep. We tend to go through four or five 90- to 110-minute rounds of this basic quiet/active sleep cycle each night. Sleepiness and alertness all the day, but which causes those patterns. Sleep is regulated and altered by two body systems either sleep or wake homeostasis and the circadian biological clock.
A growing number of "clock genes" have been identified that play a critical role in mammalian circadian timing. In addition, there is clear evidence that non-suprachiasmatic nucleus (SCN) tissues have clock genes and can demonstrate circadian rhythms. Thus, circadian modulation occurs both centrally and peripherally, further emphasizing the importance of circadian chronobiology in the timing of sleep and waking as well as a wide variety of physiologic functions. These studies of clock genes also apply to humans, in particular patients with advanced sleep phase syndrome, especially prominent in the elderly population. The role of endogenous melatonin in the sleep/wake cycle has been better defined and the clinical studies on the role of exogenous melatonin to treat sleep disorders are on-going.
OMICS International through its Open access initiatives is committed to make genuine and reliable contributions to the scientific community by publishing research work and conference paper related to such disorders. It is known that OMICS Group hosts over 700 edge peer reviewed Open Access Journals and organizes over more than 1000 Global Events annually. Its publishing group journals have over 5 million readers and the fame and success of the same can be attributed to the strong editorial board which contains over 75000+ eminent personalities that ensure a quality and quick review process checker.
Scope and importance
When we have been awake for a long period of time, sleep or wake homeostasis tells us that a need for sleep is accumulating and that it is time to sleep now. This also helps us to maintain enough sleep throughout the night to make up for the hours of being awake. If this restorative process existed alone, it would mean that we would be most alert as our day was starting out, and that the longer we were awake, the more we would feel like sleeping. This way, sleep/wake homeostasis creates a drive that balances sleep and wakefulness.
In body sleep is regulated by two systems. They are circadian biological clock, and sleep/wake homeostasis. Sleep/wake homeostasis tells us that a need for sleep is accumulating and that it is time to sleep, when we have been awake for a long period of time, and It also helps us maintain enough sleep throughout the night to make up for the hours of being awake. This restorative process existed. It will alert as our day was starting, and the longer we were awake, the more we would feel like sleeping. So in this way, sleep/wake homeostasis creates a drive that balances sleep and wakefulness.
On the other hand, circadian biological clock, regulate the timing of periods of sleepiness and wakefulness. Circadian rhythm dips and rises at different times of the day, so adults strongest sleep drive generally occurs between 2:00-4:00 am and in the afternoon between 1:00-3:00 pm, there might be some variation depending on whether you are a “morning person” or “evening person.” The sleepiness we experience during these circadian dips will be less intense if we have had sufficient sleep, and more intense when we are sleep deprived. The circadian rhythm also causes us to feel more alert at certain points of the day, even if we have been awake for hours and our sleep/wake restorative process would otherwise make us feel sleepier.
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The Neurobiology of Sleep and Circadian Rhythm
Sleep Down Under
Sleep and breathing
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List of major Sleep Disorders related Research Centres
Armenian sleep disorders association
Austrian sleep research association
Belgian association for sleep research and sleep medicine
British sleep society
Bulgarian sleep society
Croatian sleep research association
Czech sleep research and sleep medicine society
Danish society for sleep medicine
Dutch society for sleep and wake research
Estonian sleep medicine association
Finnish sleep research society
French society for sleep research and sleep medicine
German society for sleep research and sleep medicine
Hellenic sleep research association
Hungarian society for sleep medicine
Increasing geriatric population coupled with rising prevalence of chronic disorders are some of the major factors driving the growth of Circadian Rhythm Sleep disorder(CRSD) market globally. Geographically, North America and Europe accounted for the largest share of the global CRSD market owing to increasing geriatric population and rising prevalence of chronic diseases. According to Eurostat (European Commission) report in 2013, around 17.8% of the European population was above the age of 65 years. Thus, this increase in geriatric population propels the growth of CRSD in European region.
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This page was last updated on 11th Sep, 2015
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